The accurate measurement of neutron skin thickness of Pb by the PREX Collaboration suggests a large value of the nuclear symmetry energy slope parameter, , whereas the smaller is preferred to account for the small neutron-star radii from NICER observations. To resolve this discrepancy between nuclear experiments and astrophysical observations, new effective interactions have been developed using relativistic mean-field models with the isoscalar- and isovector-meson mixing. We investigate the effects of -nucleon coupling and – mixing on the ground-state properties of finite nuclei, as well as the characteristics of isospin-asymmetric nuclear matter and neutron stars. Additionally, we explore the role of the quartic -meson self-interaction in dense nuclear matter to mitigate the stiff equation of state for neutron stars resulting from the large -nucleon coupling. It is found that the nuclear symmetry energy undergoes a sudden softening at approximately twice the saturation density of nuclear matter, taking into account the PREX-2 result, the recent NICER observation of PSR J04374715, and the binary neutron star merger, GW170817.

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