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The pion light-cone distribution amplitude (LCDA) is a central non-perturbative object of interest for high-energy exclusive processes in quantum chromodynamics. In this article, the second Mellin moment of the pion LCDA is determined as a proof-of-concept calculation for the first numerical implementation of the heavy-quark operator product expansion (HOPE) method. The resulting value for the second Mellin moment, determined in quenched QCD at a pion mass of MeV at a factorization scale of 2 GeV is $ \langle \xi^2 \rangle = 0.210 \pm 0.013 \pm 0.034$. This result is compatible with those from previous determinations of this quantity.

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