This article presents differential measurements of the asymmetry between and baryon production rates in proton-proton collisions at centre-of-mass energies of and collected with the LHCb experiment, corresponding to an integrated luminosity of . The baryons are reconstructed through the inclusive semileptonic decay . The production asymmetry is measured both in intervals of rapidity in the range and transverse momentum in . The results are found to be incompatible with symmetric production with a significance of 5.8 standard deviations for both and data, assuming no violation in the decay. There is evidence for a trend as a function of rapidity with a significance of 4 standard deviations. Comparisons to predictions from hadronisation models in PYTHIA and heavy-quark recombination are provided. This result constitutes the first observation of a particle-antiparticle asymmetry in -hadron production at LHC energies.

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