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We present a generalization of Descartes’ theorem for the family of polytopal sphere packings arising from uniform polytopes. The corresponding quadratic equation is expressed in terms of geometric invariants of uniform polytopes which are closely connected to canonical realizations of edge-scribable polytopes. We use our generalization to construct integral Apollonian packings based on the Platonic solids. Additionally, we also introduce and discuss a new spectral invariant for edge-scribable polytopes.

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