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We discuss the Mayer-Vietoris spectral sequence as an invariant in the context of persistent homology. In particular, we introduce the notion of -acyclic carriers and -acyclic equivalences between filtered regular CW-complexes and study stability conditions for the associated spectral sequences. We also look at the Mayer-Vietoris blowup complex and the geometric realization, finding stability properties under compatible noise; as a result we prove a version of an approximate nerve theorem. Adapting work by Serre we find conditions under which -interleavings exist between the spectral sequences associated to two different covers.

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