Let be an irreducible imprimitive subgroup of , where is a field. Any system of imprimitivity for can be refined to a nonrefinable system of imprimitivity, and we consider the question of when such a refinement is unique. Examples show that can have many nonrefinable systems of imprimitivity, and even the number of components is not uniquely determined. We consider the case where is the wreath product of an irreducible primitive $H \leq \operatorname{GL}_d()K \leq S_kn = dk$. We show that has a unique nonrefinable system of imprimitivity, except in the following special case: , is even, , and is a transitive subgroup of . As a simple application, we prove results about inclusions between wreath product subgroups.

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