The Cartan-Hadamard conjecture states that, on every -dimensional Cartan-Hadamard manifold , the isoperimetric inequality holds with Euclidean optimal constant, and any set attaining equality is necessarily isometric to a Euclidean ball. This conjecture was settled, with positive answer, for . It was also shown that its validity in dimension ensures that every -Sobolev inequality () holds on with Euclidean optimal constant. In this paper we address the problem of classifying all Cartan-Hadamard manifolds supporting an optimal function for the Sobolev inequality. We prove that, under the validity of the -dimensional Cartan-Hadamard conjecture, the only such manifold is , and therefore any optimizer is an Aubin-Talenti profile (up to isometries). In particular, this is the case in dimension . Optimal functions for the Sobolev inequality are weak solutions to the critical -Laplace equation. Thus, in the second part of the paper, we address the classification of radial solutions (not necessarily optimizers) to such a PDE. Actually, we consider the more general critical or supercritical equation where . We show that if there exists a radial finite-energy solution, then is necessarily isometric to , and is an Aubin-Talenti profile. Furthermore, on model manifolds, we describe the asymptotic behavior of radial solutions not lying in the energy space , studying separately the -stochastically complete and incomplete cases.

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