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The pairing symmetry of superconducting infinite-layer nickelates is a fundamental yet experimentally challenging question. We employ high-energy electron irradiation to induce disorder in superconducting NdSrNiO thin films and examine the impact of pair-breaking defects on superconductivity and elucidate the nature of the superconducting gap. Our measurements reveal a complete suppression of superconductivity with increasing disorder, suggesting an unconventional, sign-changing order parameter.

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