We consider the indefinite Sturm-Liouville differential expression where is defined on a finite or infinite open interval with $0\in Irwr(x)(\operatorname{sgn} x) w(x)I$. With the differential expression we associate a nonnegative self-adjoint operator in the Krein space , which is viewed as a coupling of symmetric operators in Hilbert spaces related to the intersections of with the positive and the negative semi-axis. For the operator we derive conditions in terms of the coefficients and for the existence of a Riesz basis consisting of generalized eigenfunctions of and for the similarity of to a self-adjoint operator in a Hilbert space . These results are obtained as consequences of abstract results about the regularity of critical points of nonnegative self-adjoint operators in Krein spaces, which are couplings of two symmetric operators acting in Hilbert spaces.

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