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We investigate the well-posedness in the generalized Hartree equation $iu_t + \Delta u + (|x|^{-(N-\gamma)} \ast |u|^p)|u|^{p-2}u=0x \in ^N0<\gamma<Np<2$. We establish the local well-posedness for a class of data in weighted Sobolev spaces, following ideas of Cazenave and Naumkin [6]. This crucially relies on the boundedness of the Riesz transform in weighted Lebesgue spaces. As a consequence, we obtain a class of data that exists globally, moreover, scatters in positive time. Furthermore, in the focusing case in the -supercritical setting we obtain a subset of locally well-posed data with positive energy, which blows up in finite time.

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