We construct a top-down holographic model of Weyl semimetal states using -dimensional supersymmetric Yang-Mills theory, at large and strong coupling, coupled to a number of hypermultiplets with mass . A subgroup of the R-symmetry acts on the hypermultiplet fermions as an axial symmetry. In the presence of a constant external axial gauge field in a spatial direction, , we find the defining characteristic of a Weyl semi-metal: a quantum phase transition as increases, from a topological state with non-zero anomalous Hall conductivity to a trivial insulator. The transition is first order. Remarkably, the anomalous Hall conductivity is independent of the hypermultiplet mass, taking the value dictated by the axial anomaly. At non-zero temperature the transition remains first order, and the anomalous Hall conductivity acquires non-trivial dependence on the hypermultiplet mass and temperature.

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