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The liquid-based detectors are widely used in particle and nuclear physics experiments. Due to the fixed way of constructing geometry in detector simulation such as Geant4, it is usually difficult to describe the non-uniformity of liquid in detectors. We propose a method based on GDML and tessellated detector description to share the detector geometry information between Computational Fluid Dynamics (CFD) simulation software and detector simulation software. The method makes it possible to study the impact of liquid flow and non-uniformity on some key performance of the liquid-based detectors, such as event vertex reconstruction resolution. It will also be helpful in detector design and performance optimization.

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