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In this paper, we prove the uniform nonlinear structural stability of Poiseuille flows with arbitrarily large flux for the Navier-Stokes system in a two dimensional periodic strip when the period is not large. The key point is to establish the a priori estimate for the associated linearized problem via the careful analysis for the associated boundary layers. Furthermore, the well-posedness theory for the Navier-Stokes system is also proved even when the external force is large in . Finally, if the vertical velocity is suitably small where the smallness is independent of the flux, then Poiseuille flow is the unique solution of the steady Navier-Stokes system in the periodic strip.

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