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In this short note, we compute the precise asymptotics for the number of contingency tables with non-uniform margins. More precisely, for parameter , we consider the set of matrices whose first rows and columns have sum and the rest rows and columns have sum . We compute the precise asymptotics of the cardinality of this set when using the maximal entropy methods developed by Barvinok and Hartigan. The only contribution of this note is a detailed expansion of the determinant of quadratic forms in asymptotic formulas.

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