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We try to justify rigorously, using a Wong-Zakai approximation argument, the susceptible-infected-susceptible (SIS) stochastic differential equation proposed in [2]. We discover that according to this approach the “right” stochastic model to be considered should be the Stratonovich version of the It^o equation analyzed in [2]. Surprisingly, this alternative model presents the following feature: the threshold value characterizing the two different asymptotic regimes of the solution coincides with the one describing the classical SIS deterministic equation.

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