Let $A=\left( \begin{array}{cc} A & 0 \ 0 & A \ \end{array}
\right)bethe2\times2$ diagonal operator matrix determined by a positive
bounded operator A. For semi-Hilbertian operators X and Y, we first show
that \begin{align*} w^2_{A}\left(\begin{bmatrix} 0 & X \ Y & 0
\end{bmatrix}\right) &\leq \frac{1}{4}\max\Big{{\big|XX^{\sharp_A} +
Y^{\sharp_A}Y\big|}{A}, {\big|X^{\sharp_A}X + YY^{\sharp_A}\big|}{A}\Big}
- \frac{1}{2}\max\big{w_{A}(XY), w_{A}(YX)\big}, \end{align*} where
wA(⋅), ∥⋅∥A and wA(⋅) are the
A-numerical radius, A-operator seminorm and A-numerical radius,
respectively. We then apply the above inequality to find some upper bounds for
the A-numerical radius of certain 2×2 operator matrices. In
particular, we obtain some refinements of earlier A-numerical radius
inequalities for semi-Hilbertian operators. An upper bound for the
A-numerical radius of 2×2 block matrices of semi-Hilbertian
space operators is also given.