This article presents a new approach of semigroup analysis and pseudo-differential calculus for deriving the regularizing estimate on non-cutoff linearized Boltzmann equation. We are able to obtain regularizing estimate of semigroup that is continuous from weighted Sobolev space to with a sharp large time decay. With these properties, we prove the existence of global-in-time unique solution to the non-cutoff Boltzmann equation for hard potential on the whole space with weak regularity assumption on initial data. We consider the hard potential case since can be embedded in . This work develops the application of pseudo-differential calculus, spectrum analysis and semigroup theory to non-cutoff Boltzmann equation.

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