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We are concerned with nonnegative solutions to the Cauchy problem for the porous medium equation with a variable density and a power-like reaction term with . The density decays {\it fast} at infinity, in the sense that as with In the case when , if is bigger than , we show that, for large enough initial data, solutions blow-up in finite time and for small initial datum, solutions globally exist. On the other hand, in the case when , we show that existence of global in time solutions always prevails. The case of {\it slowly} decaying density at infinity, i.e. , is examined in [41].

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