Using a data sample corresponding to an integrated luminosity of , collected by the LHCb experiment, the production of the state in proton-proton collisions at a centre-of-mass energy of is studied in the rapidity range and in the transverse momentum range . The cross-section for prompt production of mesons relative to that of the meson is measured using the decay mode and is found to be ${\sigma_{\eta_c(1S)}/\sigma_{J/\psi} = 1.69 \pm 0.15 \pm 0.10 \pm 0.18}$. The quoted uncertainties are, in order, statistical, systematic and due to uncertainties on the branching fractions of the and decays. The prompt production cross-section is determined to be ${\sigma_{\eta_c(1S)} = 1.26 \pm 0.11\pm 0.08 \pm 0.14 ,\mu b}{J/\psi}b$-hadron decays to the and states is measured to be ${{b\to\eta_c X}/{b\to J/\psi X} = 0.48 \pm 0.03 \pm 0.03 \pm 0.05}$, where the last uncertainty is due to those on the branching fractions of the and decays. The difference between the and masses is also determined to be , which is the most precise single measurement of this quantity to date.

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