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In this paper, we are concerned with the well-posedness and large time behavior of Cauchy problem for 3D incompressible Navier-Stokes-Cahn-Hilliard equations. First, using Banach fixed point theorem, we establish the local well-posedness of solutions. Second, assuming is sufficiently small, we obtain the global well-posedness of solutions. Moreover, the optimal decay rates of the higher-order spatial derivatives of the solution are also obtained.

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