In this work, the Cauchy problem for the semilinear Moore-Gibson-Thompson (MGT) equation with power nonlinearity on the right-hand side is studied. Applying estimates and a fixed point theorem, we obtain local (in time) existence of solutions to the semilinear MGT equation. Then, the blow-up of local in time solutions is proved by using an iteration method, under certain sign assumption for initial data, and providing that the exponent of the power of the nonlinearity fulfills for and for . Here the Strauss exponent is the critical exponent for the semilinear wave equation with power nonlinearity. In particular, in the limit case a different approach with a weighted space average of a local in time solution is considered.

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