Artificial confinement of electrons by tailoring the layer thickness has turned out to be a powerful tool to harness control over competing phases in nano-layers of complex oxides. We investigate the effect of dimensionality on transport properties of -electron based heavy-fermion metal CaCuRuO. Transport behavior evolves from metallic to localized regime upon reducing thickness and a metal insulator transition is observed below 3 nm film thickness for which sheet resistance crosses $h/e^{2} \sim 25~\Omega$, the quantum resistance in 2D. Magnetotransport study reveals a strong interplay between inelastic and spin-orbit scattering lengths upon reducing thickness, which results in weak antilocalization (WAL) to weak localization (WL) crossover in magnetoconductance.

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