We investigate the robustness against disorder of superconductivity in multiband systems where the fermions have four internal degrees of freedom. This permits unconventional -wave pairing states, which may transform nontrivially under crystal symmetries. Using the self-consistent Born approximation, we develop a general theory for the effect of impurities on the critical temperature, and find that the presence of these novel -wave channels significantly modifies the conclusions of single-band theories. We apply our theory to two candidate topological superconductors, YPtBi and CuBiSe, and show that the novel -wave states display an enhanced resilience against disorder, which extends to momentum-dependent pairing states with the same crystal symmetry. The robustness of the -wave states can be quantified in terms of their superconducting fitness, which can be readily evaluated for model systems.

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