We demonstrate that mass inequalities for hadrons with one or more heavy quarks arise primarily from the concavity of binding energies in the quark model, reflecting short-range Coulombic interactions and long-range confinement. Empirical two-body bindings are extracted from spin-averaged meson masses, ensuring model independence and direct use of experimental data. Fitting these as functions of reduced mass reveals a critical confinement scale of 1.34~fm where bindings turn positive. The concave justifies Jensen-like inequalities under flavor permutation, reproducing relations like and baryon analogs, including . Hadron mass decomposition validates with ~MeV for mesons and baryons. Promoting inequalities to equalities, we predict masses for unobserved heavy baryons (e.g., MeV, MeV and MeV) and identify favored quark-exchange scattering channels.

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