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In this paper, we show that every -vertex induced subgraph of the -dimensional cube graph has maximum degree at least . This result is best possible, and improves a logarithmic lower bound shown by Chung, F"uredi, Graham and Seymour in 1988. As a direct consequence, we prove that the sensitivity and degree of a boolean function are polynomially related, solving an outstanding foundational problem in theoretical computer science, the Sensitivity Conjecture of Nisan and Szegedy.

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