Let be a f.g. discrete group and let be a Galois -covering of a smooth closed manifold . Let be the analytic structure group, appearing in the Higson-Roe analytic surgery sequence $\to S_^\Gamma(\tilde M)\to K_(M)\to K_(C_r^\Gamma)\to$. We prove that for an arbitrary discrete group it is possible to map the whole Higson-Roe sequence to the long exact sequence of even/odd-graded noncommutative de Rham homology $\to H_{[-1]}(\Gamma)\to H^{del}_{[-1]}(\Gamma)\to H^{e}_{[]}(\Gamma)\to\GammaC^_r\Gamma$. Here, is the delocalized homology and is the homology localized at the identity element. Then, under additional assumptions on , we prove the existence of a pairing between , the delocalized part of the cyclic cohomology of , and . This, in particular, gives a pairing between and . We also prove the existence of a pairing between and the relative cohomology . Both these parings are compatible with known pairings associated with the other terms in the Higson-Roe sequence. In particular, we define higher rho numbers associated to the rho class of an invertible -equivariant Dirac type operator on . Finally, we provide a precise study for the behavior of all previous K-theoretic and homological objects and of the higher rho numbers under the action of the diffeomorphism group of . Then, we establish new results on the moduli space of metrics of positive scalar curvature when is spin.

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