Results from proton-lead and fixed-target collisions at LHCb

The latest results obtained by the LHCb collaboration from proton-lead and proton-gas fixed-target collisions are presented. Results related to charm and beauty flavour hadron and quarkonia production in proton-lead collisions, being clean probes for Cold Nuclear Matter effects, are compatible to predictions based on initial-state effects. Indications of significant final-state effects in excited $\mathrm{{\rm Y}}(nS)$ resonances production are reported. The first cross-section measurement of $c\bar{c}$ and antiproton production in fixed-target proton-helium collisions at 100 GeV energy scale are also presented. More results will come from the latest Run 2 and future Run 3 data.