In this article we study transitions and possible correlations with the anomalous magnetic moment of the muon () within two-Higgs-doublet models with generic Yukawa couplings, including the possibility of right-handed neutrinos. We perform the matching on the relevant effective Hamiltonian and calculate the leading one-loop effects for $b\to s\ell\ell^{(\prime)}b\to s\gamma\Delta B=\Delta S=2b\to s\nu\bar\nu\ell\to\ell^\prime\gammaR_\xi$ gauge. Concerning the phenomenology, we find that an explanation of the hints for new physics in data is possible once right-handed neutrinos are included. If lepton flavour violating couplings are allowed, one can account for the discrepancy in as well. However, only a small portion of parameter space gives a good fit to data and the current bound on requires the mixing between the neutral Higgses to be very small if one aims at an explanation of .

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