In the present paper, we consider the following singularly perturbed problem: \begin{equation*} \left{ \begin{array}{ll} -\varepsilon^2\triangle u+V(x)u=\varepsilon^{-\alpha}(I_{\alpha}F(u))f(u), & x\in \R^N; u\in H^1(\R^N), \end{array} \right. \end{equation} where is a parameter, , , and $I_{\alpha}: \R^N\rightarrow \R$ is the Riesz potential. By introducing some new tricks, we prove that the above problem admits a semiclassical ground state solution () and a ground state solution () under the general “Berestycki-Lions assumptions” on the nonlinearity which are almost necessary, as well as some weak assumptions on the potential . When , our results generalize and improve the ones in [V. Moroz, J. Van Schaftingen, T. Am. Math. Soc. 367 (2015) 6557-6579] and [H. Berestycki, P.L. Lions, Arch. Rational Mech. Anal. 82 (1983) 313-345] and some other related literature. In particular, our approach is useful for many similar problems.

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