Ultralight dark matter can behave as a coherent background field and induce time-dependent modifications of Standard Model parameters. We study a scenario in which a real ultralight scalar couples off-diagonally to down-type quarks, linking ultralight dark sectors to flavor physics. Working within an effective field theory, we diagonalize the quark mass matrix in a coherent background and derive analytic expressions for oscillatory shifts in down-type quark masses and CKM parameters. These effects lead to signatures in both the classical regime, where acts as a background field, and the quantum (particle) regime, where it contributes through on-shell production or off-shell mediation. Using precision flavor measurements, nuclear decays, atomic clocks, pulsar timing, and meson observables, we derive constraints on the flavor-violating couplings for –, highlighting the complementarity of time-domain and flavor probes of ultralight dark sectors.

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