Both the neutron skin thickness of atomic nuclei and the low-energy neutrino-nucleon () interactions are of fundamental importance in nuclear and particle physics, astrophysics as well as new physics beyond the standard model (SM) but largely uncertain currently, and the coherent elastic neutrino-nucleus scattering (CENS) provides a clean way to extract their information. New physics beyond the SM may cause effectively a shift of the SM weak mixing angle in low-energy interactions, leading to an effective weak mixing angle . By analyzing the CENS data of the COHERENT experiment, we find that while a one-parameter fit to the COHERENT data by varying produces fm for CsI with an unrealistically large central value by fixing at the low-energy SM value of , a two-dimensional fit by varying and leads to a strong positive correlation between and with significantly smaller central values of $\Delta R^{\rm {CsI}}{np} \simeq 0.24{-2.03}^{+2.30}\sin^2 \theta^W = 0.21{-0.10}^{+0.13}$. Although the uncertainty is too large to claim a determination of $\Delta R^{\rm{CsI}}_{np}\sin^2 \theta^_W$, the present study suggests that the multi-dimensional fit is important in future analyses of high-precision CENS data. The implication of the possible deviation of $\sin^2 \theta^*_W\sin^2\theta_W^{\rm{SM}}$ on new physics beyond the SM is also discussed.

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