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In this paper we introduce new symmetrization with respect to mixed volume or anisotropic curvature integral, which generalizes the one with respect to quermassintegral due to Talenti and Tso. We show a P'olya-Szego type principle for such symmetrization – it diminishes the anisotropic Hessian integral for quasi-convex functions. We achieve this by a systematic study of invariants on non-symmetric matrices with real eigenvalues and the higher order anisotropic mean curvatures of level sets, which may be of independent interest. As applications, we establish a comparison principle for anisotropic Hessian equations and sharp anisotropic Sobolev inequalities.

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