We propose a unifying theoretical framework for the analysis of first-passage time distributions in two important classes of stochastic processes in which the diffusivity of a particle evolves randomly in time. In the first class of “diffusing diffusivity” models, the diffusivity changes continuously via a prescribed stochastic equation. In turn, the diffusivity switches randomly between discrete values in the second class of “switching diffusion” models. For both cases, we quantify the impact of the diffusivity dynamics onto the first-passage time distribution of a particle via the moment-generating function of the integrated diffusivity. We provide general formulas and some explicit solutions for some particular cases of practical interest.

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