We calculate the contribution of the meson exchange process generated by the Cabibbo-Kobayashi-Maskawa matrix to the electric dipole moment (EDM) of the Be nucleus by considering the $\alpha n - \alpha \Lambda$ channel coupling. It is found that the effect of the Pauli exclusion principle is not important intermediate state, and that the result is consistent with the EDM of Be calculated with the interactions as a perturbation without considering the nucleus-hypernucleus mixing. Our result suggests that the effect of the interactions is neither suppressed nor enhanced in nuclei, if the difference of binding energies between the nucleus and the hypernucleus is small compared to the hyperon-nucleon mass difference.

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