Let be a smooth bounded domain in and denote the regular part of the Green’s function on with Dirichlet boundary condition as . Assume that and . We prove that there exists an integer such that for any integer there exist initial data and smooth parameter functions , $0<\mu(t)\to 0t\to +\inftyu_q$ of the critical nonlinear heat equation \begin{equation*} \begin{cases} u_t = \Delta u + |u|^{\frac{4}{n-2}}u \Omega\times (0, \infty),\ u = 0 \partial \Omega\times (0, \infty),\ u(\cdot, 0) = u_0 \Omega, \end{cases} \end{equation*} has the form \begin{equation*} u_q(x, t) \approx \mu(t)^{-\frac{n-2}{2}}\left(Q_k\left(\frac{x-\xi(t)}{\mu(t)}\right) - H(x, q)\right), \end{equation*} where the profile is the non-radial sign-changing solution of the Yamabe equation \begin{equation*} \Delta Q + |Q|^{\frac{4}{n-2}}Q = 0^n, \end{equation*} constructed in \cite{delpinomussofrankpistoiajde2011}. In dimension 5 and 6, we also prove the stability of .

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