We make an attempt to study the impact of renormalization-group equations (RGE) induced reflection symmetry breaking on the effective Majorana neutrino mass in neutrinoless double beta () decay. At present, the decay serves as a unique process to address the Majorana nature of massive neutrinos. The rate of such decay process depends on . On the other hand, reflection symmetry predicts and $ \delta = \pm 90^\circ \rho, \sigma $). Moreover, based on the recent global best-fit values which prefer higher octant of and third quadrant of , it is hard to believe the exactness of such symmetry. Also, any non-trivial values of may have some significant impact on . In this context, we study the spontaneous breaking of the symmetry via one-loop RGE-running from a superhigh energy scale () down to the electroweak scale (). Given the broken symmetry, we perform some systematic analysis for in substantial detail. Further, we also extend this analysis for other lepton-number violating effective Majorana masses.

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