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In this work we give a sharp criterion for the global well-posedness, in the energy space, for a system of nonlinear Schr"odinger equations with quadratic interaction in dimension . The criterion is given in terms of the charge and energy of the ground states associated with the system, which are obtained by minimizing a Weinstein-type functional. The main result is then obtained in view of a sharp Gagliardo-Nirenberg-type inequality.

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