We propose a homological approach to the Cohen–Macaulayness problem for orbit closures in varieties of quiver representations. Given a finite quiver , a dimension vector , and a representation , we relate the Cohen–Macaulay property of the orbit closure to the projective dimension of its coordinate ring as a module over the polynomial algebra . For tree quivers, we obtain a numerical criterion expressing Cohen–Macaulayness in terms of the projective dimension of , the dimension of the representation variety, and the dimension of the endomorphism algebra of . This viewpoint recasts known results for Dynkin quivers of types and and suggests a possible homological strategy for the remaining exceptional Dynkin types.

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