We derive the partition function of 5d gauge theories on the manifold with a partial topological twist along the Riemann surface, . This setup is a higher dimensional uplift of the two-dimensional A-twist, and the result can be expressed as a sum over solutions of Bethe-Ansatz-type equations, with the computation receiving nontrivial non-perturbative contributions. We study this partition function in the large limit, where it is related to holographic RG flows between asymptotically locally AdS and AdS spacetimes, reproducing known holographic relations between the corresponding free energies on and and predicting new ones. We also consider cases where the 5d theory admits a UV completion as a 6d SCFT, such as the maximally supersymmetric Yang-Mills theory, in which case the partition function computes the 4d index of general class theories, which we verify in certain simplifying limits. Finally, we comment on the generalization to ${\cal M}3 \times \Sigma{\frak g}{\cal M}_3$ and focus in particular on , in which case the partition function relates to the entropy of black holes in AdS.

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