We study the helicity distributions of light flavor quark-antiquark ($q \bar{q}$) pairs in the nucleon sea. The valence quarks are handled by adopting the light-cone SU(6) quark-spectator-diquark model and the sea pairs are treated from statistical consideration by introducing the helicity suppression factors and to parametrize the helicity distributions of q-flavor sea quark and antiquark respectively, while $\Delta l_q(x)=l_q(x)-\bar l_q(x)$ represents a combined effect of helicity contribution due to sea pairs. From fitting the nucleon polarization asymmetries in inclusive deep inelastic scattering processes and the single-spin asymmetries in Drell-Yan type processes, we find a significant asymmetry between the quark and antiquark helicity distributions of the nucleon sea. Therefore the quark-antiquark asymmetry of helicity distributions of nucleon sea pairs, i.e., , plays an important role for a comprehensive understanding of the nucleon spin content.

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