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In this paper we prove the fractional Gagliardo-Nirenberg inequality on homogeneous Lie groups. Also, we establish weighted fractional Caffarelli-Kohn-Nirenberg inequality and Lyapunov-type inequality for the Riesz potential on homogeneous Lie groups. The obtained Lyapunov inequality for the Riesz potential is new already in the classical setting of . As an application, we give two-sided estimate for the first eigenvalue of the Riesz potential. Also, we obtain Lyapunov inequality for the system of the fractional -sub-Laplacian equations and give an application to estimate its eigenvalues

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