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We consider the focusing -supercritical fractional nonlinear Schr"odinger equation where $d\geq 2, \frac{d}{2d-1} \leq s <1\frac{4s}{d}<\alpha<\frac{4s}{d-2s}$. By means of the localized virial estimate, we prove that the ground state standing wave is strongly unstable by blow-up. This result is a complement to a recent result of Peng-Shi [J. Math. Phys. 59 (2018), 011508] where the stability and instability of standing waves were studied in the -subcritical and -critical cases.

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