In this paper, we study the anisotropy of cosmic acceleration the using Pantheon sample, which includes 1048 spectroscopically confirmed Type Ia supernovae (SNe Ia) covering the redshift range . In hemisphere comparison method, we find the dipole direction is $(l = 37 \pm 40^{\circ}, b = 33 \pm 16^{\circ})\delta=0.136 {}^{+0.009}{-0.005}$. From the dipole fitting method, we find that the magnitude of anisotropy is , and the direction of the dipole $(l = 329^{\circ}{}^{+ 101^{\circ}}{-28^{\circ}}, b = 37^{\circ}{}^{+ 52^{\circ}}_{-21^{\circ}})$ in the galactic coordinate system. The result is weakly dependent on redshift from the redshift tomography analysis. The anisotropy is small and the isotropic cosmological model is an excellent approximation.

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