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Two-loop self-energy corrections to the bound-electron factor are investigated theoretically to all orders in the nuclear binding strength parameter . The separation of divergences is performed by dimensional regularization, and the contributing diagrams are regrouped into specific categories to yield finite results. We evaluate numerically the loop-after-loop terms, and the remaining diagrams by treating the Coulomb interaction in the electron propagators up to first order. The results show that such two-loop terms are mandatory to take into account for projected near-future stringent tests of quantum electrodynamics and for the determination of fundamental constants through the factor.

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