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This paper is concerned with the blowup criterion for mild solution to the incompressible Navier-Stokes equation in higher spatial dimensions . By establishing an regularity criterion, we show that if the mild solution with initial data in , becomes singular at a finite time , then The corresponding result in 3D case has been obtained by I.Gallagher, G.S.KochandF.Planchon. As a by-product, we also prove a regularity criterion for the Leray-Hopf solution in the critical Besov space, which generalizes the results in~\cite{DoDu09}, where blowup criterion in critical Lebesgue space is obtained.

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