Achieving Analytical and Cellular Control in Confined Spaces and Continuous Flow

Sabeth Verpoorte is professor at the University of Groningen. In this contribution she describes the development of a microfluidic incubation system for drug metabolism studies using a “top-down” precision-cut tissue slice model. She also outlines a fundamental particle separation concept, which relies on the generation of controlled bi-directional flow in microchannels having variable cross-sectional dimensions, by opposing pressure-driven and electrokinetic flows.