Quantum interference phenomena in superconductors, such as Josephson interference and Little-Parks oscillations, serve as powerful probes of phase coherence, symmetry breaking and vortex dynamics. However, they are typically observed in well-defined mesoscopic structures, and their behavior in the two-dimensional limit remains largely unexplored. Here, we report periodic magnetoresistance oscillations, superconducting interference patterns, and interfering diode effect in unpatterned few-layer NbSe2. These phenomena emerge exclusively within the superconducting fluctuation regime of thin samples, consistent with the enhanced anomalous metallic behavior of atomically thin NbSe2. The non-monotonic temperature dependence of both the oscillation amplitude and the diode efficiency can be captured by a model in which thermally activated vortices traverse intrinsic supercurrent loops. Our results reveal that the observed interference phenomena originate from the lost of global phase coherence, providing a new route to accessing interference effects in unpatterned superconductors.

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