We investigate a nonlocal equation in , where is unbounded and belongs to a weighted space. Crucial weighted and interpolation estimates for the Green operator are established by a new method based on the sharp Young’s inequality, the asymptotic behavior of a regular varying coefficients exponential series, and the properties of auxiliary functions that and $\eta^{-b_+/2}\lesssim\varGamma/\left\langle x\right\rangle^b\lesssim \eta^{-b_-/2}\phi_R=\varGamma\eta=R$) instead of principal eigenfunctions. Global well-posedness in weighted spaces for the Cauchy problem is proved. When the Fujita exponent is shown to be . Our approach generalizes and unifies nonlocal diffusion equations and pseudoparabolic equations.

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