We report measurements of charm-mixing parameters based on the decay-time-dependent ratio of to rates. The analysis uses a data sample of proton-proton collisions corresponding to an integrated luminosity of fb recorded by the LHCb experiment from 2011 through 2016. Assuming charge-parity (CP) symmetry, the mixing parameters are determined to be , $y’=(5.28 \pm 0.52) \times 10^{-3}R_D=(3.454 \pm 0.031)\times10^{-3}$. Without this assumption, the measurement is performed separately for and mesons, yielding a direct CP-violating asymmetry $A_D =(-0.1\pm9.1)\times10^{-3}1.00< |q/p| <1.3568.3%$ confidence level. All results include statistical and systematic uncertainties and improve significantly upon previous single-measurement determinations. No evidence for CP violation in charm mixing is observed.

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