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We investigate a non-homogeneous nonlinear heat equation which involves degenerate or singular coefficients belonging to the class of functions. We prove the existence of a Fujita exponent and describe the dichotomy existence/non-existence of global in time solutions. The coefficient admits either a singularity at the origin or a line of singularities. In this latter case, the problem is related to the fractional laplacian, through the Caffarelli-Silvestre extension and is a first attempt to develop a parabolic theory in this setting.

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